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KMID : 0861420120160020110
Korean Journal of Nuclear Medicine Technology
2012 Volume.16 No. 2 p.110 ~ p.114
Evaluation of Image Quality Based on Time of Flight in PET/CT
Lim Jung-Jin

Yoon Seok-Hwan
Kim Jong-Pil
Park Sang-Ryoon
Shin Seong-Hwa
Yun Sang-Hyeok
Kim Yeong-Seok
Lee Hyeong-Jin
Lee Hong-Jae
Kim Jin-Eui
Woo Jae-Ryong
Abstract
Purpose: PET/CT is widely used for early checking up of cancer and following up of pre and post operation.
Image reconstruction method is advanced with mechanical function. We want to evaluate image quality of each
reconstruction program based on time of flight (TOF).

Materials and Methods:After acquiring phantom images
during 2 minutes with Gemini TF (Philips, USA), Biograph mCT (Siemens, USA) and Discovery 690 (GE,
USA), we reconstructed image applied to Astonish TF (Philips, USA), ultraHD ¡¤ PET (Siemens, USA), Sharp
IR (GE, USA) and not applied. inside of Flangeless Esser PET phantom (Data Spectrum corp., USA) was filled
with 18F-FDG 1.11 kBq/ml (30 ¥ìCi/ml) and 4 hot inserts (8. 12. 16. 25 mm) were filled with 8.88 kBq/ml (240
¥ìCi/ml) the ratio of background activity and hot inserts activity was 1 : 8. Inside of triple line phantom (Data
Spectrum corp., USA) was filled with 18F-FDG 37 MBq/ml (1 mCi). Three of lines were filled with 0.37 MBq
(100 ¥ìCi). Contrast ratio and background variability were acquired from reconstruction image used Flangeless
Esser PET phantom and resolution was acquired from reconstruction image used triple line phantom.
Results: The contrast ratio of image which was not applied to Astonish TF was 8.69, 12.28, 19.31, 25.80% in phantom lid of which size was 8, 12, 16, 25 mm and it which was applied to Astonish TF was 6.24, 13.24, 19.55, 27.60%.
It which was not applied to ultraHD ¡¤ PET was 4.94, 12.68, 22.09, 30.14%, it which was applied to ultraHD ¡¤
PET was 4.76, 13.23, 23.72, 31.65%. It which was not applied to SharpIR was 13.18, 17.44, 28.76, 34.67%, it
which was applied to SharpIR was 13.15, 18.32, 30.33, 35.73%. The background variability of image which was
not applied to Astonish TF was 5.51, 5.42, 7.13, 6.28%. it which was applied to Astonish TF was 7.81, 7.94, 6.40
6.28%. It which was not applied to ultraHD ¡¤ PET was 6.46, 6.63, 5.33, 5.21%, it which was applied to ultraHD
¡¤ PET was 6.08, 6.08, 4.45, 4.58%. It which was not applied to SharpIR was 5.93, 4.82, 4.45, 5.09%, it which
was applied to SharpIR was 4.80, 3.92, 3.63, 4.50%. The resolution of phantom line of which location was upper,
center, right, which was not applied to Astonish TF was 10.77, 11.54, 9.34 mm it which was applied to Astonish
TF was 9.54, 8.90, 8.88 mm. It which was not applied to ultraHD ¡¤ PET was 7.84, 6.95, 8.32 mm, it which was
applied to ultraHD ¡¤ PET was 7.51, 6.66, 8.27 mm. It which was not applied to SharpIR was 9.35, 8.69, 8.99, it
which was applied to SharpIR was 9.88, 9.18, 9.00 mm.

Conclusion: Image quality was advanced generally while reconstruction program which is based on time of flight was used. Futhermore difference of result compared each manufacture reconstruction program showed up, however this is caused by specification of instrument of each manufacture and difference of reconstruction algorithm. Therefore we need further examination to find out appropriate reconstruction condition while using reconstruction program used for
advance of image quality.
KEYWORD
Time of Flight(TOF), Contrast ratio, Background variability, Resolution
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